Posts by: Jose Marques Lopes, PhD

News

Anxiety, learning difficulties, and behavior problems are the main areas of concern in patients with fragile X syndrome (FXS), according to a survey that included patients, family members or caregivers, ... Read more

December 5, 2018December 5, 2018

Ability to Form Words, Sentences Linked with Autism Spectrum Disorder Severity in Young Males with Fragile X

News

A greater ability to generate words, phrases and sentences correlates with lower autism spectrum disorder (ASD) symptom severity in adolescent and young adult males with fragile X syndrome (FXS), according ... Read more

November 27, 2018November 27, 2018

Mavoglurant Safe, Well-tolerated Long-term in Adolescents and Adults with Fragile X Syndrome, Studies Show

News

Mavoglurant is safe and well-tolerated in the long-term to treat adolescents and adults who have fragile X symptoms. The investigational compound also is associated with positive efficacy results, according ... Read more

October 25, 2018October 26, 2018

Changes in Calcium Dynamics Within Nerve Cells May Be Biomarker for Fragile X, Study Reports

News

Altered calcium levels and poorly regulated activity in specific calcium channels in nerve cells could underlie fragile X syndrome (FXS) and be used as a diagnostic and treatment biomarker, ... Read more

September 19, 2018September 19, 2018

IL-6 Molecule May Be Behind Abnormal Nerve Cell Communication in Fragile X, Study Suggests

News

High levels of a pro-inflammatory molecule called interleukin (IL)-6 in the brain could be key to abnormal neuronal communication in fragile X syndrome, a mouse study reports. The study, ... Read more

May 29, 2018May 29, 2018

Researchers Awarded $100K Grant to Study Reversal of Fragile X Symptoms

News

A University of Calgary team attempting to reverse symptoms of fragile X syndrome (FXS) in mice was awarded a $100,000 grant by the FRAXA Research Foundation and the Fragile X Research ... Read more

March 27, 2018March 27, 2018

FDA Grants Fast Track Designation to OV101 for Fragile X

News

The U.S. Food and Drug Administration (FDA) recently granted fast track designation to Ovid Therapeutics’ Fragile X syndrome (FXS) treatment candidate OV101 (gaboxadol). The designation accelerates the development and ... Read more

March 20, 2018March 20, 2018

Zynerba to Start Trial of Its Fragile X Syndrome Therapy in Mid-2018

News

Zynerba Pharmaceuticals will start a clinical trial of its cannabis-based Fragile X syndrome treatment ZYN002 in mid-2018. The U.S. Food and Drug Administration gave the company a green light for the trial ... Read more

March 13, 2018March 13, 2018

DNA Mutation Linked to Impaired Motor Skills in Children on the Autism Spectrum

News

A certain type of DNA mutation is related to impaired motor skills in children with autism spectrum disorders (ASD), including fragile X. The research behind that finding, “Damaging de ... Read more

February 1, 2018

Inflexible Learning Disability in Fragile X Syndrome Explained in New Mouse Study

News

Mice with the genetic defect that causes fragile X syndrome (FXS) are unable to learn new information that contradicts what they initially learned, researchers at NYU and the State ... Read more

Posts by: Jose Marques Lopes, PhD

Jose Marques Lopes, PhD

Anxiety, Learning and Behavior Issues Top Concerns in Fragile X Syndrome, Survey Shows

Ability to Form Words, Sentences Linked with Autism Spectrum Disorder Severity in Young Males with Fragile X

Mavoglurant Safe, Well-tolerated Long-term in Adolescents and Adults with Fragile X Syndrome, Studies Show

Changes in Calcium Dynamics Within Nerve Cells May Be Biomarker for Fragile X, Study Reports

IL-6 Molecule May Be Behind Abnormal Nerve Cell Communication in Fragile X, Study Suggests

Researchers Awarded $100K Grant to Study Reversal of Fragile X Symptoms

FDA Grants Fast Track Designation to OV101 for Fragile X

Zynerba to Start Trial of Its Fragile X Syndrome Therapy in Mid-2018

DNA Mutation Linked to Impaired Motor Skills in Children on the Autism Spectrum

Inflexible Learning Disability in Fragile X Syndrome Explained in New Mouse Study

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