Posts by: Joana Carvalho, PhD

Joana Carvalho, PhD

Joana holds a BSc in Biology, a MSc in Evolutionary and Developmental Biology and a PhD in Biomedical Sciences from Universidade de Lisboa, Portugal. Her work has been focused on the impact of non-canonical Wnt signaling in the collective behavior of endothelial cells — cells that made up the lining of blood vessels — found in the umbilical cord of newborns.

July 14, 2020July 14, 2020

Understanding Changes in Synapses May Provide Therapeutic Clues for Fragile X, Mouse Study Suggests

News

Scientists found evidence of a decoupling between structural and functional changes that weaken synapses (the place where nerve cells communicate). The findings may help identify new therapeutic targets and ... Read more

April 14, 2020April 14, 2020

Antipsychotic Medication Trifluoperazine Shows Promise for Fragile X, Study Finds

News

Trifluoperazine, an approved antipsychotic medication normally prescribed to treat schizophrenia and anxiety, may be a promising therapeutic candidate for people with fragile X syndrome, a new study suggests. The ... Read more

February 13, 2020February 13, 2020

Scientists Discover Molecular Process Linking Fragile X and Autism

News

Researchers have discovered that the fragile X mental retardation protein (FMRP) — the key protein lacking in fragile X syndrome — interacts with small fragments of a gene called eIF4G ... Read more

February 11, 2020February 11, 2020

Mouse Model Shows Auditory Impairments Similar to Patients with Fragile X, Study Says

News

A mouse model of fragile X syndrome shows mild auditory impairments resembling those seen in people with the disorder, a study found. The study, “Characterization of auditory and binaural ... Read more

January 9, 2020January 9, 2020

Results of Phase 2 Trial Testing OV101 in Fragile X Expected Later This Year

News

Ovid Therapeutics is expecting to have data from a Phase 2 trial testing OV101 (gaboxadol) in teenagers and young adults with fragile X syndrome later this year. The main goal of ... Read more

December 3, 2019December 3, 2019

Fish Model of Fragile X Suggests Early Critical Time Window for Treatment, Study Shows

News

A new animal model of fragile X syndrome suggests that a short time window very early in life is critical for effectively treating the condition. The study, “A DNAzyme ... Read more

November 21, 2019November 21, 2019

Study Lends Support for Fragile X Genetic Screening in All Pregnant Women

News

Genetic screening for fragile X syndrome should be available to all pregnant women and to those considering having a child, regardless of family history or fertility issues, a study ... Read more

October 8, 2019October 9, 2019

Derivatives of Alzheimer’s Disease Precursor May be Valuable Biomarkers of Disease Activity in Fragile X, Study Suggests

News

Derivatives of an Alzheimer’s disease precursor may be valuable biomarkers of disease activity in fragile X syndrome, according to a recent study. The results of the study, “Peripheral Amyloid ... Read more

September 26, 2019September 26, 2019

Caregivers Validate Scale Used to Assess Behaviors of Children with Fragile X

News

Most caregivers claim that children with fragile X syndrome (FXS) show signs of social avoidance, unresponsiveness or lethargy and irritability, confirming the utility of a set of subscales traditionally ... Read more

September 19, 2019September 19, 2019

Signaling Cascade Discovered in Fruit Flies May Be Promising Target for FXS Therapy

News

Scientists have discovered a signaling cascade in fruit flies that may be a promising therapeutic target for treating fragile X syndrome in humans. The study with that finding, “Wnd/DLK Is ... Read more

Pin It on Pinterest