Clues to Treating Fragile X Come From Altered Gene Regulation Process

Alterations in a genetic quality control mechanism due to loss of FMRP — fully known as fragile X mental retardation protein — may provide clues as to how healthy function might be restored to cells affected by fragile X syndrome. The study detailing this finding, “Loss…

Study Links Missing Protein to Fragile X Patients’ Hypersensitivity to Sound

The fragile X mental retardation protein plays a role in the development of the hearing system, a study in mice reports. This could explain why people with fragile X syndrome, which is caused by the loss of the FMRP protein, are hypersensitive to sound, researchers said. In normal circumstances, the FMR1…